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Sunday, September 19, 2010

New perspectives in the rich geological complexity of the Moon

Moon geologically is more complex than previously thought, scientists reported on September 17 in two articles published in the journal also Science.See: space & TimeMoonSpace MissionsNASASpace exploration space ProbesPlutoReferenceLunar space ElevatorMeteoriteEclipseMoon

His conclusion is based on data from the experiment of the lunar radiometer soothsayer aboard NASA Lunar Reconnaissance Orbiter (LRO), not manned fully entera.La Moon spacecraft orbits associate some 31 miles from the surface of the moon.

New numbers previously invisible compositional differences in the Highlands crust of the moon to reveal and have confirmed the elements silicon and oxygen - material the existence of surprisingly rich in silica - substance containing in five regions of moles.

All minerals and therefore each rock absorbed and radiates energy with a unique spectral signature that can be measured, to his identity.For the first time in history reveal, dowser provides scientists with global, high-resolution maps infrared Moon, allow you to a final identification of silicates, often in the bark found.

Co-authors in the research include David Paige, principal investigator who drive soothsayer and Professor at the UCLA in Planetologie, Benjamin green Germany, a scientist at the laboratory of NASA received at UCLA in Paige; Timothy Glotch, an associate professor of Geosciences, the University of New York Stony Brook; and Paul Hayne, that his Ph.d. at UCLA this year see Paige to get.

Lunar geology can generally be divided into two categories: the Highlands, the anorthosite containing an igneous rock that rich that calcium, aluminium and Maria (Latin for "sea"), basalt, rich in iron and observations of the soothsayer magnesio.Las volcanic igneous rock are confirmed that more land moles accordance with compositions, but divided into two broad Categorías.Sin spectral signatures, you have also showed that the Highlands can be less homogeneous than I thought.

In a variety of fields, magician revealed the presence of Lunar soil compositions, rich in sodium anorthosite Típico.ESTOS soil crust reveals that there have been changes in the chemical industry and speed Ocean can cooling magma, which made the early Lunar crust, or "Processing" (point melt and solidify repeatedly) early lunar crust, said green, Germany.

Multi-site dowser has detected the presence of minerals that are found only in conjunction with rocks, extensive magmatic process - are exposed to, these are very silica, quartz, rich in potassium feldspar minerals and rich in sodium feldspar, the common mineral rock formed in the Earth's crust.

Siliceous minerals detection at these sites is one find meaningful because you in areas previously shown to display highly unusually high frequencies of thorium element, a proxy for occur lithologies, developed Paige said.

"" Silícicas features we've found on the moon are essential from the typical basaltic Mare and Highlands anorthosite, "said Glotch, lead author of one of the documents.""We see, these multiple configurations geological composition suggests that there have been several processes of production of these rocks can".

Steep slopes have some high silica, regions such as trafficking in human beings Gruithiusen and rough, surfaces - like dome in St. Helens, after the eruption formed said Glotch of lava domes can suggesting that they are created by the slow eruption viscous lava on the lunar surface.

In other regions, such as the crater Aristarchus siliceous spectral signatures are limited to craters and material ejected by his impacto.Esto that the excavation of the underground by these effects caused has suspended parts of PLUTONE, the institutions of the solidified magma u-Bahn from reaching the surface proposes.

As such materials make high silica in a glass that rich is ruled basaltic through the Highlands of calcium and iron and Maria magnesium-rich anorthosite?

High siliceous sites occur in Procellarum KREEP property (PKT), an expensive the mole area which was known for its wide basáltico.Esto volcanism scientists believe that material rich in silica present in this region a result of the hot of basaltic magma we interfere and recasting the Lunar crust.

However, regions, Belkovich Compton, way of PKT and its associated vulcanismo.La location of Compton Belkovich beats anomaly occurs before on the far side of the Moon, that the conditions, you have to sustainable production of heat and Volcanism on the PKT resulted in many smaller scales on the far side of the moon there been can.

Not obvious thing in data is lunar coat, pristine material evidence that previous studies suggested that you at some places on the surface material, rich in iron and magnesium lunar.Dicho exposed can be easy by Soothsayer, would be discovered Paige said.

In the pole South Aitken basin (SPA), largest crater, oldest and deepest deep enough the crust and mantle - have penetrated the moon - there is however no evidence for material of a cloak, said.

This time effects are unknown; perhaps no such risks coat material, or may occur in areas too small for soothsayer to recognize that Paige said.

However, it is likely the impact that these craters formed material coat, ditch since then crustal material inside and outside of the SPA have mixed with subsequent effects.

"" New data soothsayer help select of the appropriate samples for future missions of landing zurückzugebenden pages of SPA, "says Green Germany." """We want these examples use date effects, the formation of SPA and potentially lunar coat, exploring so it is important to use data soothsayer to identify areas with a minimum of mix".

Soothsayer still detailed maps of infrared reflection and moon for the rest of the mission solar Goddard Flight Center manages LRO.El LRO Greenbelt, MD NASA.



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Researchers identify genetic markers of aggressive ad

Discovered an international team of experts from the Alzheimer's disease was under the direction of Washington University School of medicine in St. Louis —, a variation of the gene predict the rate in which ad will also be progress.See: health & MedicineAlzheimer ResearchHealthy AgingDiseases and ConditionsChronic with Lewy BodiesDementiaHuntington DiseaseMenopause IllnessElder CareStroke PreventionReferenceDementia

Researchers report their findings online in the journal public library of Science (PLoS)-gene.

While previous studies have focused on the factors that influence the risk for ad, new points that determine a way to research how quickly develop complete dementia Alzheimer's patients after his diagnosis.

A protein called Tau researchers studied 846 patients with elevated privileges in the cerebrospinal fluid (CSF) .Estudios last found that the presence of a particular form the dew in CSF protein an indicator of Alzheimer Krankheit.Die researchers saw also unique DNA variations in patients and identify a genetic marker in connection with high tau.This tags that output to a rapid progression of Alzheimer's disease are associated with.

"" People institution of this genetic marker tend to higher levels of Tau have at any time the disease as individuals without it, "said senior researcher Alison M. Goate, DPhil, the Samuel and Mae S. Ludwig Professor of genetics in psychiatry.""Until now most of the risks which has genetic studies with Alzheimer's disease risk for developing the disease, not the speed with which once you have identified genetic markers as we tiene.El progression notes the progress looked."

For many patients and their families more useful than that this information may know a person can develop Alzheimer's disease, even if that person has developed clinical signs yet as Goate brain damage.Damage caused by the disease can for years, before symptoms appear.But exist that proposes this study that Tau high, combined with genetic markers could be a signal that can quickly move the clinical symptoms of mild impairment in severe dementia.

The study progress that recent research found that it possible diagnosis is Alzheimer's disease even in patients without clinical symptoms by measuring the levels of the protein beta amyloid in CSF.A beta of senile plaques in the brain of Alzheimer's patients, but it is low in the CSF A beta predict the presence of Alzheimer's disease in the brain pathology.

Meanwhile, the Tau protein accumulates to characterize the disease in the abnormal brain structures, called neurofibrilares.Los tangles cause clutter the brain cells die and Tau is released the presence of the disease when the cells die, in the Cefalorraquídeo liquid.Only low level of A beta of the CSF display associated high dew.

"Tau in stroke patients or with other types of lesions of the brain can be started," says first author Carlos Cruchaga, PhD. "but a particular form the dew specifically for Alzheimer.Es disease a form phosphorylated protein is called Ptau." "As Parkinson's disease not Ptau produce neuro-degenerative diseases high GFK.nur in Alzheimer's disease found."

Cruchaga, Assistant Professor of Psychiatry at the University of Washington, said that there was no relationship between Ptau and overall risk of Alzheimer's disease or age of onset for Alzheimer's patients, but there was a significant association between a variant of a gene, that plays a role for the change of Tau protein Ptau in the framework for community support and the rate of disease levels was promoting.

"" We examined data from three independent, international studies and three, we find the same Association, "said Cruchaga." """So, that we sure that it is real and that this variant of the gene are associated with the progression of Alzheimer's disease".

Says the genetic discovery, combined with the ability, measuring Ptau of CSF can mean if drugs that could inhibit accumulation of protein in the liquid may hinder or delay some havoc with Alzheimer's disease combined.

"If somehow we Tau could reduce Pathology at those individuals also small amounts of GfK, A beta, we the progression of the disease can slow down", says Cruchaga.

Goate said that the conclusions of first useful Clínicos.Si studies who knew in advance design researchers could be specific study patients at a pace would move faster, you could better assess the impact of drugs, designed to slow progression of Alzheimer's disease.

"" I believe that if the objective of the drug is A beta, below, must really begin treatment even before someone develops symptoms, "Goate said.""Instead, since most occurs changes in the dew if someone already has symptoms, possible this way to the progression of the disease, to slow down by interfering with the actions of Tau protein to go."



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Saturday, September 18, 2010

Less is more in the fight against terrorism

Terrorist networks are complex. Now, a mathematical analysis of its characteristics published this month in International Journal of networks and virtual organizations, suggested that the best way to fight, is the hub from network, instead of trying to destroy to isolate the network as a whole on short-term battles.See: media in mind & BrainSocial PsychologyIntelligenceComputers & MathComputer ModelingComputer ProgrammingScience & SocietyConflictPrivacy IssuesReferenceLocal NetworkMathematical model computer SimulationStreaming area

According to Philip Vos Fellman Professor at Suffolk University, Boston, and a member of the Institute for complex systems of New England, USA tools that are used to analyze complex systems also can be used to study the terrorist networks to undermine.

Vos Fellman explains terrorist networks are "with typical structures in the study of the conflict in the sense that do not have several recyclable complexity and ambiguity levels."

"This complexity is exacerbated by the covert activities of terrorist networks, where key elements during longer can remain hidden, and the network itself is dynamic," adds Vos Fellman, expert in strategy and modeling which is matemática.La nature of a dynamic network similar to the Internet robust but contrasts with the structure of the armed forces or security of the homeland, which tend be centralized and hierarchical.

Vos Fellman has used network based on agent, landscapes of fitness NK Boolean attempt dynamic simulation analysis.In given the complexity of terrorist networks to understand, it focuses on how long-term operational and strategic planning could do, so they provide tactics that seem to avoid immediate if little long-term damage terrorist network impact cause.

Computer Vos Fellman terrorist network simulations suggest that isolation, instead of reducing could be key to successfully defeat.

"" "" "Results that this simulation and dynamic systems are the modeling tools to recommend that literally, sometimes less is more, says Vos Fellman", and the operational objectives could be better oriented isolation instead of remove ".auch should evidence that simulations that show smooth or simple, small cells within a network objectives for the most part, not worth perseguir.En instead efforts are to focus the hub to the network depends.""If you focus on the important questions focused, then says the opportunity cost considerations suggest that it would be best to do, nothing, rather than spending valuable resources in exercises that doomed."



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Protein can regulate blood stem cells: new hope future treatments for leukemia

Researchers have discovered that a protein can regulate certain features of the blood, patients.See better could lead the treatment of leukemia stem cells: cell health & MedicineStem CellsProstate CancerLeukemiaBrain TumorLymphomaAnemiaReferenceStem TreatmentsBone TransplantBone bone marrow stem cells MarrowEmbryonic

Discovery - by Dr. Tarik Möröy, President and Chief Scientific Officer and Director of unit research hematopoiesis and Cancer Institute recherches cliniques de Montreal (IRCM) and his team - recent blood, Official Journal of the American Society of Hematología.Dr.Cyrus Khandanpour, doctor of medicine and postdoctoral fellow in the laboratory of Dr. Möröy, is the first author of the study.

Worldwide a blood stem cell transplant therapy used for patients with leukemia and other blood diseases. "Given for Leukemia patients blood stem cells location of renewal of blood are all production system and all its cells of the blood, including the white blood cells, red blood cells and platelets," explains Dr. Möröy.

First patients with leukemia or a blood disorder with chemotherapy that destroyed handles your complete form system, together with disease blood.Blood stem cells then, in two ways used diferentes.El can first is to give you harvest the patient before chemotherapy and pushed their own cells mother following treatment can reconstruct the blood cells."" One of the problems with this therapy is that blood stem cells are normally in a niche between bone and surrounding cells and are in a latent state ", explains Dr. Khandanpour." "To obtain a sufficient number of stem cell niche bone marrow have mobilized from your be, before you enter the bloodstream where can easily be picked up."

"The latter is a patient the harvesting of a healthy donor blood stem cells, and you, after treatment.These foreign cell then rebuild chemotherapy to regenerate the patient blood system and their blood cells."However, this therapy still fails in about 10%-20% of cases, ", adds Dr. Khandanpour." "These patients die out among other things, that transplanted stem cells new blood cells not fast enough what generate infection and death."

"" We found a protein (called Gfi1b), which appears to regulate the level of activity of stem cells and which are in the bone ", says Dr. Khandanpour. "In our mouse model we could disable Gfi1b gene encoding."If we did, cells mother converted enabled, began to expand dramatically, left his niche of the bone marrow and entered into the bloodstream without its function."this way blood stem cells change significantly increase the effectiveness of stem cell therapy."

The production of new blood cells could accelerate however to more efficient and less dangerous according to the inactivation of the Gfi1b in transplanted stem cells the researchers for paciente.Sin stem cell therapy, mechanisms of regulation of cells latency mother and mobilization are not well understood.

"Next goal" is our to investigate the molecular mechanisms that requires ablation Gfi1b, and to more accurately to explore mother, as it regulates when Gfi1b to the location and the activation of blood cells,"adds Dr. Möröy.""Our project will contribute to a better understanding of the biology of stem cell mobilization and latency which might lead the design of better treatment therapies for transplant donor and patient".

According to the information about the Leukemia & Lymphoma Society of Canada, a person is diagnosed with blood cancer every four minutes, and someone dies of cancer of the blood that every 10 minutos.Esta figure representing more than 54,000 people per year. leukemia caused more deaths than any other cancer in children and young adults under the age of 20.

This research project was supported by the Canadian Institutes of research health (Canadian), Canada Research Chair and the Cole Foundation program.



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Veterinarian says natural foods not always best for pets

An increasing trend among people during the natural foods, should farmers after to a veterinarian of Kansas State University be careful of feed with similar types of food for your pets. Susan Nelson, Assistant Professor of clinical services.See K Estado also said all owners that too often to take pets are the basis of certain foods, like fruits and vegetables, healthy for you, including your pets healthy: psychiatric service dog from implant (tier) plants & AnimalsFoodDogsVeterinary MedicineAgriculture and FoodOrganicBacteriaReferenceCompanion DogHypoallergenicMicrochip

"Veggie-based pet and natural foods based more demand on the market of the owner, not because you necessarily better for the dog," he said.

Natural pet food is not necessarily insecure pets, and there are good brands on the market.But dogs and cats have specific nutritional needs, some of these foods cannot provide Nelson said.

Antioxidants from fruits and vegetables can offer such as a natural dog food, but may be deficient in other nutrients you need owner the perro.Si pet opt for natural pet food, it is important to ensure, that a balanced diet said pets get.

And buy, all pet food that labeled natural owner is sure that should comes from a known Firma.Nelson, said that sets the Association of American feed control officials AAFCO, guidelines for the production, labelling and distribution of pet food and for nutritional adequacy diets minimum standards.

Ensure that food included need sufficient nutrients for a pet, pet owners should only buy food for pets that has at least one of the two statements of nutritional suitability of AAFCO on its label, said Nelson.Mapping rules determine whether the product of pet food company complete and balanced to a stage of life, the specific according to one of two criteria: diet formula meets the minimum nutritional requirements by the Association imported or diet Association, feeding studies has suffered.

Generally makes, test while it is not perfect, give the best assessment of what as well is the food be carried out for a certain stage, said Nelson.Owners Declaration makes on must be examined closely the label, some food for intermittent feeding or for specific life stages are designed and detrimental for a pet if long-term fed.

It is important to distinguish between the terms how natural, organic and holistic.Organic and holistic is currently has no specific definitions for pet food in accordance with the guidelines of the Association of American feed control officials.Organic defined by the Ministry of Agriculture of the United States for human consumption, but the Department has no definition of natural food for people, said Nelson.

Power control Association defines natural products such as those that chemically do not contain any ingredients synthesized vitamins or minerales.Las tags natural products containing any of these ingredients declared: "Natural with added vitamins, minerals and other nutrients, the track" should .Verbraucher carefully a company that claims to have organic food or holistic because there is no definition of the partnership, said Nelson pet food.

Consumers should pay attention to the ingredients of the example alimentos.Por, cats and dogs should not eat onion or ajo.Mientras, linseed oil can provide fatty acids for dogs, cats for this purpose used werden.sollten no manufacturer that uses these ingredients, Nelson said.

"" Most reputable companies veterinary nutritionists on page "said Nelson.""These companies perform also nutritional research and have their own internal quality control".

Because preservatives, often debate need dry pet food are the best artificial preservatives or naturales.Estudios show that synthetic preservatives seem work better and not bad pet's layers that contain, but in the alimentos.Sin demand of the market for the use of vitamins E and C, you natural preservative.

How each diet pet who choose natural food for pets pet owner should make an eye on your pets ensure that food is not affecting Nelson said.

"Suppose the diet you have chosen meets minimum standards for nutritional adequacy AAFCO and if your dog is healthy, the coat quality, good body is State good faecal consistency and is able to do their work, the diet is enough for him, probably," he said.



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Popular additions to fight pain in the joints work, study finds

Two popular additions accepted by millions of people around the world to combat pain in the joints, no work, research published online in the British Medical Journal.

Supplements Glucosamine and Chondroitin are by osteoarthritis in the knees and hips own hit or in combination, to reduce the pain.

Researchers led by Professor Peter Jüni at the University of Bern in Switzerland, so you argue that regarding these additions are not dangerous "We see with who as long they prepared as you continue to perceive no harm an advantage and cover the cost of treating yourself".

However, added: "health authorities and health insurers must not cover the cost of these preparations and new recipes for patients who should have received no treatment be discouraged".

Say arthrosis of the hip or knee is a chronic disease, mainly with pain medications and drugs non-steroidal anti-inflammatory, but you can the heart and stomach problems, especially if long plazo.tratamientos, which not only the pain to reduce, but slows the progression of the disease it desirable, the authors.

In the last decade GPS and rheumatologists have increasingly more Glucosamine and Chondroitin for your patients.And prescribed, which bought many people around the world have revenues of Glucosamine supplements that reached almost $ 2,000, an increase of 60% since 2003 in the 2008 contador.En worldwide.

The authors say the results from existing studies on the effectiveness of Glucosamine and Chondroitin, contradictorios.Por are therefore requires a review a large-scale studies to determine whether or additions are not working.

Professor Jüni and his colleagues analyzed the results of published studies 10 3803 patients with osteoarthritis knee or cadera.Evaluaron changes once the patients took Glucosamine, Chondroitin, or their combination with placebo or head to head pain levels.

Found no clinically relevant effects of chondroitin, glucosamine, or their combination in perceived pain articulate joints or space narrowing.

Despite this observation, some patients are convinced that these preparations are advantage, you say the autores.Ellos suggest that this may be because the natural course of osteoarthritis or the placebo effect.

Connect "when compared to placebo, glucosamine, Chondroitin and their combination not reduce pain in the joints or affect the articular.Las place the narrowing of the health authorities and health insurers must discourage funding of the treatment of Glucosamine and Chondroitin,".



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Friday, September 17, 2010

Even very low dose aspirin regular neighborhoods outside of colorectal cancer, study finds

Even at the lowest dose aspirin (75 mg) from the colon cancer ward, if taken regularly, research Gut.

This protective effect arises after only one year and the general public, not only for those who usually run development of disease risk to kill the second leading cause of cancer death in the world, half a million people each year.

While previous research shown that aspirin against colorectal cancer protects, is not known what is the most effective dose and how much time needs to be taken.

The research team investigated nearly 2,800 people with colorectal cancer and fair than 3,000 healthy people who equalised by age, sex and residence.

All participants completed to assess the frequency of food and lifestyle questionnaires their usual diet and lifestyle that are known to affect the risk of bowel cancer options.

Inclusion of NSAIDs (non steroidal drugs anti-inflammatory) was categorized as more than four tablets per month of low dose aspirin (75 mg), other NSAIDs, or a mixture.

The probability of survival colorectal cancer diagnosed once or to develop the disease was persecuted again once more than five years.

Brought together 354 (15.5%) of people that healthy with colorectal cancer of low-dose aspirin versus 526 (18%) of their peers.

Take regularly all NSAIDs, slow down the chances of developing bowel cancer compared with those who take this pain.

This statement instead of true, regardless of age, diet, weight, deprivation and lifestyle options

After a year with daily low dose aspirin aspirin it assigned a lower risk of 22% for colorectal cancer and the extent of the risk reduction was cumulative to reach 30% after five years.

1170 People died from total 3,417 who diagnosed with colorectal cancer with (including those that were healthy start of the study) while most of these deaths (1023) disease due were the seguimiento.La.

Information on the use of NSAIDs was available from 676 1,023 deaths and showed the NSAIDs of any influence had none on the risk of death for some reason, nor has the survival increase of colorectal cancer.

But above all results show that aspirin taken Ward high doses for a long time not helping from colorectal cancer, say the authors.



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