The randomized clinical trial of two years is the largest effect of B vitamins in mild cognitive impairment, and one of the first disease-modifying tests have shown relating to Alzheimer's disease to study positive results in people.
About 1 in 6 of 70 oldest has mild cognitive impairment, problems with memory, language or other psychological functions, but not to a degree which hampered life diaria.Alrededor half of people with mild cognitive impairment develop dementia - especially the disease of Alzheimer's - is five years of diagnosis.
Certain vitamins B, folic acid, vitamin B6, vitamin B12 - are known to treat the amino acids in the blood homocysteine levels and high homocysteine associated with an increased risk of Alzheimer's disease.
Therefore, to see Oxford if B vitamins supplements the highest rate of contraction of the brain or atrophy, can lower homocysteine observed in mild slow the team cognitive impairment or Alzheimer's disease.
168 Study followed 70 years old, or with mild memory, Tablet-high doses of vitamin B for two years and half of whom placebo tableta.Los volunteers researchers took half rated the progression of the disease in this group, using MRI to the brain during a period of two years measuring atrophy rate analysis.The results in the journal PLoS ONE are published.
The team found that on average folic acid, vitamin B6 and B12 treatment reduces the brains of who to 0.76 percent per year, while those in the placebo group had an average 1,08%.Personas with highest homocysteine benefited brain shrink ratio again showing atrophy treatment rates were half of the people with placebo.
The team investigate together at the rate of contraction of the brain from the Oxford project manager memory and Aging (OPTIMA) cared cognitive test results reveal that more achieved those with the most slow pace of contraction.
The team proposed that, since the rate of cerebral atrophy is known to be, the fastest people with mild cognitive impairment, which will develop Alzheimer's disease is possible that vitamin treatment development of disease.Now that can slow down clinical studies are carried out, to test this, adds.
«It is our hope that it delayed mild memory, easy and safe treatment to the development of Alzheimer's disease in many people, the suffering ", said David Smith, Professor of the Department of Pharmacology at Oxford University, a co-leader of the trial."» "»Today there are 1.5 million older people in the UK, 5 million in the United States and 14 million in Europe with such memory issues.
«Are immensely promising results, but you need to do, close more tests if these B vitamins persons may slow down or prevent developing the Alzheimer.Por disease yet to recommend that that each a little old and beginning is concerned about memory lapses should hurry up and buy vitamin supplements without seeing a doctor, ' said.»
Rebecca wood, Executive Director of the Alzheimer's disease research trust, which funded the study, said: "these are very important results, vitamin B complex that protect a perspective on some of the Alzheimer's disease in the strong conclusions vejez.Las now shows more expected man who inspired to Alzheimer's disease develop and we must hope an extended essay that more successful."
"We urgently need to support research on dementia, the massive increase in people with the condition of aging of the population to vermeiden.Forschung is the only answer to what is still the largest medical challenge of our time.
Professor Chris Kennard, Professor of neuroscience and the Council of mental health, which co-finances the study, the Medical Research Council said: "reject MRC funded this study us one step closer to the complex of the Neurobiology of aging and cognitive to unravel, the key to the development of future treatments for conditions is as disease Alzheimer.Los results are promising and we hope that more research is necessary to check if the B complex vitamins as appropriate treatment may be recommended. '"
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